C14 STUDIES IN CARBOHYDRATE METABOLISM

Studies on Carbohydrate Metabolism

Previous studies of carbohydrate metabolism have been limited almost exclusively to naturally occurring saturated sugars. Very little attention has been devoted to the fate of the unsaturated and anhydro sugars in the organism. Even though these unsaturated sugars occur very rarely in nature, information concerning their fate in the body would be of value in determining the mechanism of sugar m...

Cl4 STUDIES IN CARBOHYDRATE METABOLISM

After a single injection of uniformly labeled glucose-Cl4 into rats (1) and dogs (2), the specific activity of plasma glucose, highest immediately after the injection, declines exponentially. The decline is due to a progressive replacement of the tagged compound with relatively non-labeled glucose. The slope or rate constant of the decay curve denotes the rate of turnover of the glucose pool ex...

C ’ ” studies in carbohydrate metabolism . IV .

SHIPLEY,REGINALD A., NOMEBAKER, GENEVIEVE E. INCEFY AND RICHARD E. CLARK. Cl4 studies in carbohydrate metabolism. IV. Characteristics of bicarbonate pool system in the rat. Am. J. Physiol. q(1): 4’-46* q5g* -Specific activity curves of expired air were obtained after the injection of NaHCY403 into normal and alloxan diabetic rats in the postabsorptive and fasted state. The curves were analyzabl...

Metabolism of Coprostanol-c14 and Cholestanol-4-c14 in Man.

NMR studies of compartmentalized cerebral carbohydrate metabolism

Localized 13C nuclear magnetic resonance (NMR) spectroscopy provides a unique window for studying cerebral carbohydrate metabolism through, e.g. the completely non-invasive measurement of cerebral glucose and glycogen metabolism. In addition, label incorporation into amino acid neurotransmitters such as glutamate (Glu), GABA and aspartate can be measured providing information on Krebs cycle flu...